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C-H Activation: Summary and Further Reading

C–H bond functionalisation has been a subject of vigorous research over the last 20 years, and more recently with respect to the development of methods that overcome the drawbacks highlighted.

Recommended reading:

I. J. S. Fairlamb, Pd-catalysed Cross-couplings for the Pharmaceutical Sector and a Move to Cutting-edge C–H Bond Functionalization: Is Palladium Simply Too Precious?, in Green and Sustainable Medicinal Chemistry: Methods, Tools and Strategies for the 21st Century Pharmaceutical Industry, L. Summerton, H. F. Sneddon, L. C. Jones and J. H. Clark, Royal Society of Chemistry, Cambridge, UK, 2016, ch. 11, pp. 129-139.

J. Wencel-Delord, T. Droge, F. Liu and F. Glorius, Towards mild metal-catalyzed C-H bond activation, Chem. Soc. Rev., 2011, 40, 4740-4761.

S. Hwan Cho, J. Young Kim, J. Kwak and S. Chang, Recent advances in the transition metal-catalyzed twofold oxidative C-H bond activation strategy for C-C and C-N bond formation, Chem. Soc. Rev., 2011, 40, 5068-5083.

S. Chandra Pan, Organocatalytic C-H activation reactions, Beilstein J. Org. Chem., 2012, 8, 1374-1384.