Enzymes from a Retrosynthetic Perspective


Following on from the previous lesson where the different enzyme classes and their mechanisms were discussed, this lesson looks at the use of these enzymes in the synthesis of certain target molecules and functional groups.  The enzymes have been systematically analysed and classified as to which functionalities can be produced from a retrosynthetic perspective.  For some functionalities a number of suitable enzymes are available that are capable of performing the transformation to produce a given functionality, in other cases only a small number of enzymes exist.


Details of enzymes

Click each reaction below to listen to Bettina Nestl talk about enzymes from a retrosynthetic perspective.

Alkenes
Amines
Alcohols
Aldehydes and Ketones
Epoxides
Imines
a-hydroxyl acids
a-hydroxyl ketones
a-hydroxyl aldehydes
Cyanohydrins
Functionalisation of Arenes
Vicinal Diols
Cyclic Compounds
Sulfoxides
Alkanes
Isomerisation