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This online resource is hosted and is being updated by the ACS GCI Pharmaceutical Roundtable. The original content was put together as part of the Innovative Medicines Initiative funded CHEM21 project (Chemical Manufacturing Methods for the 21st Century Pharmaceutical Industries), Europe’s largest public-private partnership dedicated to the development of manufacturing sustainable pharmaceuticals. One of the primary aims of this project is to promote the uptake of green and sustainable methodologies amongst both existing and future generations of medicinal and process chemists and to embed them in every day practice.

This online resource is further supplemented by a complementary book, edited and authored by CHEM21 consortium members and collaborating external experts, that addresses current challenges in modern green chemical technologies and sustainability thinking. It encompasses a broad range of topics covered by the CHEM21 project. The book, available in both hardcopy and electronic format, provides an overview of the key green chemistry tools, guidance and considerations aimed at developing greener processes, before moving on to look at cutting-edge synthetic methodologies.

Green and Sustainable Medicinal Chemistry: Methods, Tools and Strategies for the 21st Century Pharmaceutical Industry, L. Summerton, H. F. Sneddon, L. C. Jones and J. H. Clark, eds., Royal Society of Chemistry, London, UK, 2016.

Both the platform and the book are outputs of the education and training package of CHEM21. This work package was led by members of the Green Chemistry Centre of Excellence at the University of York, with contributions from across the CHEM21 consortium.


As such, the audience for this platform includes undergraduate students, postgraduates and industrial chemists (for example for new starter training and Continuing Professional Development). Although this resource has been created with a focus on ‘greening’ the synthesis of active pharmaceutical ingredients (APIs), it is also of relevance to other industries and anyone who is interested in learning more about greener methodologies. The resources are divided into two levels:

  • Introductory material that can be found in Foundation that will give the user a basic appreciation of the concepts therein;
  • More focussed and in-depth material on a range of topics.

The full list of available courses and modules is available from the home page.

How you can use the material

The intention is that the material here is a permanent resource that can be studied in various ways:

  • as a course in its own right;
  • embedded into other courses, in whole or part;
  • as individual stand-alone modules that can be chosen to suit the needs of individuals or organisations.

The material is presented in a user friendly format of ‘bite-sized’ modules. You can either run through these sequentially, or select individual areas of interest. For each of the topics there are defined learning objectives and the content is a blend of written material, videos, easy to use guides that can be adopted in every-day working and further reading. The content is supported by quizzes and more in depth exercises to test knowledge and understanding.

For more information about copyright and licensing please see our legal statements.

This resource is provided by the American Chemical Society Green Chemistry Institute Pharmaceutical Roundtable. The source material was created as part of the Innovative Medicines Initiative (IMI) funded CHEM21 project (Chemical Manufacturing Methods for the 21st Century Pharmaceutical Industries). CHEM21 received funding from the IMI Joint Undertaking under grant agreement n°115360, resources of which are composed of financial contribution from the European Union’s Seventh Framework Programme (FP7/2007-2013) and EFPIA companies’ in-kind contribution.

The educational material is licensed (unless otherwise specified) under Creative Commons license CC BY-NC 4.0, which gives permission for it to be shared and adapted for non-commercial purposes as long as attribution is given. For full details please see our legal statements.

The views expressed in regards to education and training materials represent the aspiration of the American Chemical Society, although may not always be the view of each individual organization. Referencing of external sources does not imply formal endorsement by the American Chemical Society.