Primary Manufacturing
Page coming soon
Recommended reading:
D. Ott, D. Kralisch, I. Denčić, V. Hessel, Y. Laribi, P. D. Perrichon, C. Berguerand, L. Kiwi-Minsker and P. Loeb, Life Cycle Analysis within Pharmaceutical Process Optimization and Intensification: Case Study of Active Pharmaceutical Ingredient Production, ChemSusChem, 2014, 7, 3521-3533.
W. De Soete, S. Debaveye, S. De Meester, G. Van der Vorst, W. Aelterman, B. Heirman, P. Cappuyns and J. Dewulf, Environmental Sustainability Assessments of Pharmaceuticals: An Emerging Need for Simplification in Life Cycle Assessments, Environmental Science & Technology, 2014, 48, 12247-12255.
C. Jimenez-Gonzalez and M. R. Overcash, The evolution of life cycle assessment in pharmaceutical and chemical applications – a perspective, Green Chemistry, 2014, 16, 3392-3400.
G. Wernet, S. Conradt, H. Peter Isenring, C. Jimenez-Gonzalez and K. Hungerbühler, Life cycle assessment of fine chemical production: a case study of pharmaceutical synthesis, The International Journal of Life Cycle Assessment, 2010, 15, 294-303.
D. Ott, S. Borukhova and V. Hessel, Life cycle assessment of multi-step rufinamide synthesis – from isolated reactions in batch to continuous microreactor networks, Green Chemistry, 2016, 18, 1096-1116.
- Examining the Life Cycle
- Drivers Towards Whole-process Thinking
- Challenges in Effecting Change
- LCA Examples
- Primary Manufacturing
- Secondary Manufacturing
- Packaging
- Pharmaceuticals in the Environment (PIE)
- Appendix: Carbon Footprinting Assumptions
- Examining the Life Cycle: Quiz
- Examining the Life Cycle: Summary and Further Reading
- The Fate of APIs
- Benign by Design
- Life Cycle Impacts: Summary and Further Reading