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Solvents
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Solvent Guides
Solvent Recovery
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Telescoping
Solvents: Quiz
Solvents: Study Exercises
Solvents: Summary and Further Reading
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C-H Activation
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Flow Chemistry
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Route Selection
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Introduction to Process Engineering
Route Selection and Scale Up: Case Study and Exercise
Process Safety
Reactive Hazards in Scaling Up: Case Study and Exercise
Reaction Work-up and Product Isolation
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Environmental Legislation
Abatement and Waste Treatment
Life Cycle Impacts
Examining the Life Cycle
The Fate of APIs
Benign by Design
Life Cycle Impacts: Summary and Further Reading
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Home
Foundation
Background to Green Chemistry
Introduction to the Pharmaceutical Industry
Pharmaceutical Process Chemistry
Critical Elements
Renewable Resources
Solvents
Guides and Metrics
Solvent Selection Guides
Reagent Guides
Metrics
Solvents
Use of Solvents
Issues Surrounding Solvent Use
Solvent Guides
Solvent Recovery
Alternative Solvents
Telescoping
Solvents: Quiz
Solvents: Study Exercises
Solvents: Summary and Further Reading
Synthetic Toolbox
Route Selection
Base metal Catalysis
Biocatalysis
Multicomponent Reactions
C-H Activation
Carbonylation
C-F Bond Formation
Flow Chemistry
Amidation
Synthetic Biology
CHEM21 Publications
Process Design
Route Selection
GMP
Introduction to Process Engineering
Route Selection and Scale Up: Case Study and Exercise
Process Safety
Reactive Hazards in Scaling Up: Case Study and Exercise
Reaction Work-up and Product Isolation
Design of Experiments
Environmental Legislation
Abatement and Waste Treatment
Life Cycle Impacts
Examining the Life Cycle
The Fate of APIs
Benign by Design
Life Cycle Impacts: Summary and Further Reading
About
Contact
Home
Guides and Metrics
Reagent Guides
GSK Example: Reductive Amination
Reductive Amination: Quiz
Reductive Amination: Quiz
Despite being the greenest reagent in the reductive amination guide, which potentially non-green trade off might a chemist have to make when using enzyme as a reagent?
*
Harsh conditions
Is used up during the reaction
Non-renewable
Requires dilute conditions
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Solvent Selection Guides
The Need for Solvent Selection Guidance
Criteria for Solvent Selection
In-house Selection Guides
Survey of Solvent Selection Guides
The CHEM21 Solvent Selection Guide
Solvent Guides for Specific Applications
Solvent Selection Guides: Summary and Further Reading
Solvent Selection Guides Exercise
Reagent Guides
GSK Reagent Selection Guides
Pfizer and ACS GCI Pharmaceutical Roundtable Selection Guides
GSK Acid and Base Selection Guides
GSK Example: Oxidation to Aldehydes and Ketones
GSK Example: Reductive Amination
Reagent Guides: Exercise
Reagent Guides: Summary and Further Reading
Metrics
Why Are Metrics Important?
Process Mass Intensity Metric
Efficiency Based Metrics
Further Metrics and Key Considerations
The CHEM21 Metrics Toolkit
Metrics: Summary and Further Reading
